936 CODING PROPERTIES OF Qa HYBRID GENES
نویسندگان
چکیده
From the Division of Biology, California Institute of Technology, Pasadena, California 91125; the *Department of Microbiology, University of Texas Health Science Center at Dallas, Dallas, Texas 75235; the *Department of Microbiology, University of Southern California School of Medicine, Los Angeles, California 90033; and the ~Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20205
منابع مشابه
Expression and T cell recognition of hybrid antigens with amino- terminal domains encoded by Qa-2 region of major histocompatibility complex and carboxyl termini of transplantation antigens
Coding potential of the Q6 gene from the Qa-2a region of BALB/c Crgl mice was analyzed by a combination of hybrid class I gene construction and DNA-mediated gene transfer. Recombinant genes were created by exon shuffling of the 5' coding region of the Q6 gene and the 3' coding region of a gene encoding a transplantation antigen (Kd, Dd, or Ld), or the inverse. Some of these hybrid class I genes...
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